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When talking about the causes of depression, it is important to note that while we lump everyone together as having major depressive disorder, in reality, these may be very different conditions. A person who has depression related to lack of sleep may be very different than a person who has depression related to low thyroid hormone, may be very different from someone who has depression due to poor coping skills. We generally group them together with the same term as a sort of final common pathway that they’re all showing the same symptoms, but in reality they may be very different conditions that in the future we may better understand and be able to individualize the treatment in a more specific way.