Ankylosing spondylitis can cause fluctuating symptoms despite being on medications. When symptoms worsen, it is referred to as a flare. When your joint pain significantly worsens. Flare can be adequately controlled by taking high dose non-steroidals or even steroid injection directly into the joint. Systemic corticosteroids by mouth is not recommended for this condition. After you recover from acute symptoms, you can slowly return back to normal work. During work, try to take frequent breaks for stretching exercise to reduce any joint stiffness and pain. In general, regular exercise can slow down the progression of the disease.