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Certain lifestyle choices also increase the risk of developing cancer. Excess alcohol intake, sedentary lifestyle without enough exercise, and excess weight or obesity, are linked to several cancers, including cancers of the pancreas, esophagus, liver, breast, colon, and uterus. The exact reason why obesity is linked to increased incidences of certain cancers is not entirely known, but it’s thought to be due to increased circulating levels of estrogen and insulin.