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Why do people get a DVT? There are many different causes for a DVT. Let’s review some of them. Now the first cause is a sedentary life, remaining sedentary or stationary for long periods of time, such as traveling on long flights greater than 12 hours. Another cause could be pregnancy. Pregnancy is a risk factor and pregnant patients should have special attention to this. Another factor could be certain medications. Cancers are another big topic that can cause DVTs. Oftentimes patients have predispositions from genetic reasons that make them more susceptible from having blood clots. Other factors include certain disease states like lupus or rheumatoid arthritis that make your blood thicker. Another cause could be dehydration. Other causes include having injuries. Heart failure is another etiology. Increased age. Smoking. Or a personal family history of blood clots.