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In my opinion, the only definite driver for medical attention in a man with low testosterone would be that of brittle bones or osteoporosis. The bone mineralization, or the strengthening of bones, not only depends on the commonly used bone agents available, but also the improvement of low testosterone. And it’s even been suggested that in order to help a man with low bone density, we really have to push the level of testosterone even higher than we would someone who’s just interested in sexual performance or improved energy.