Peyronie’s Disease – Risk Factors

Transcript

When thinking about the causes of Peyronie’s disease, there’s a few things we’ve learned so far, and it’s one of the things that we’re actually still learning a lot about, one of those conditions. So the first thing is, there’s a genetic predisposition to it. Generally, men of Northern European ancestry or Viking ancestry, they’re predisposed to developing these plaques and scars. And not just on their corporal bodies or their penis, but also on their hands. Something called Dupuytren’s contracture, Viking’s disease is what it is referred to as well. Another thing is tissue ischemia. Anytime there’s compromised blood flow, as a result of that, you get scarring. And with that scarring specifically to the corporal bodies, that scarring will prevent and not allow that corporal body to expand, causing penile curvature. Lastly, trauma. Trauma is a big one as well. Guys who’ve experienced anything such as a penile fracture, where that corporal body ruptures, as a result of aggressive intercourse, once that happens, that area doesn’t always heal the best way. Sometimes what happens is it heals with a scar and again, because of the pathophysiology of Peyronie’s disease, scar and plaque formation, once you develop a scar there, that area will not be able to expand the same way as the rest of the corporal body. And as a result, you get penile curvature.