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One possible event that may occur is inhalation of a poison ivy burning ivy, which may lead to difficulty breathing. Immediate medical attention is recommended if a patient experiences respiratory distress symptoms or unbearable discomfort due to poison ivy exposure. It’s also important to seek immediate medical attention if the reaction is widespread and severe. If swelling of the skin continues, if the areas involved are sensitive, such as the face, genitalia, if blisters become secondarily infected, oozing pus, if a fever develops, and of course, if the rash progresses rapidly and fails to get better.