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The typical treatments prescribed or medications used to treat poison ivy include moderate to potent topical steroids, such as triamcinolone or clobetasol ointment. Ointments are generally stronger than creams and are preferable and more inclusive, containing a stronger effect to relieve the itching. Tylenol or Motrin may be given for discomfort or to help bring down a fever. A course of oral steroids can be given in severe cases. Uncomfortable itching or extensive rashes or body surface area of involvement. In addition, anti-histamines such as Benadryl or hydroxyzine can also be given to help relieve itching. Domeboro soaks can be done at home to help cleanse the area and to prevent secondary bacterial infections. If a secondary bacterial infection occurs, a course of oral antibiotics may be necessary.