What else can cause heartburn symptoms? Well, in pregnant ladies, for example, hormones can affect the lower esophageal sphincter. It can compromise its degree of contraction, and so then the likelihood of reflux occurring is more common. Increased weight. And you can imagine if you have increased fat cells or enlarged organs in your abdomen, this will cause pressure on your lower esophageal sphincter and that will facilitate acid reflux. So these are some of the common symptoms. Now, what are some of the warning signs, things that you really would want to be concerned about? Well, if you notice that your appetite has dropped off significantly. If you’ve lost 10% of your body weight over a relatively short period of time and you’re not on a diet, that should really get your attention. If you have pain upon swallowing or if you have difficulty swallowing, these are warning signs of more severe conditions or complicated gastroesophageal reflux disease.