Let's talk about treatments of angina. We will obviously focus first on lifestyle modification and medications. So we often recommend an aspirin, a baby aspirin, or a full aspirin, depending on the physician and the patient, to treat them long-term. We often give them cholesterol lowering, not just to lower cholesterol, but to stabilize plaque. And then we give them medications such as beta blockers, or calcium channel blockers that actually reduce the workload on the heart and reduce the symptom of angina or anginal equivalent, whether it's the other symptoms we talk about. And then if these measures are not successful in controlling the patient, we often proceed to what we call diagnostic angiography, and then with plans for intervention. So you go in, you find a blockage and you think it needs to be improved. You put in a wire, you put in a balloon and then leave a stamp behind what we call PCI or percutaneouscory intervention, or stenting with those therapies. Often the patients get additional therapies such as aspirin and additional antiplatelet, and then the beta blocker, calcium channel blocker, or the alternative. If their blood pressure can't take beta blockers and calcium channel blockers we have a drug called ranolazine or Ranexa.