The risk factors of tumors is very, very minimal. And I think that there are some risk factors, but they usually are not related to the most common types of brain cancer. There are some relationships between radiation and the development of various meningiomas, or there's some people have thought about various trauma that is associated with meningiomas, but that's very, very uncommon. And for the most part, a lot of meningiomas that we see here at center for neurosciences are for the most part incidental findings on brain imaging. In terms of gliomas, the risk factors, very, very difficult to pin down. There still needs to be additional studies defining the risk factors and the factors that play into the development of gliomas.