People often ask why they develop carpal tunnel syndrome. People get carpal tunnel syndrome for a variety of reasons. Most often there’s no identifiable cause. It simply happens. In those cases, we believe that people are simply genetically predisposed to develop carpal tunnel syndrome, probably because of their anatomy. The other group of people who develop the syndrome are people who have underlying conditions. Those conditions are diabetes, rheumatoid arthritis, or other inflammatory diseases, hypothyroidism and pregnancy. The other two factors that increase the incidence of carpal tunnel syndrome are age and female gender. Women and older people get carpal tunnel syndrome more frequently.