Venous thromboembolism, meaning deep vein thrombosis and pulmonary embolism, in people's life can be dramatic. And I want to start by describing DVT and what's called post-thrombotic syndrome. When the symptoms of deep vein thrombosis, meaning pain and swelling are kept there for too long. I mean, in months or years, this may end in a condition that is highly disabling and in a condition that cannot be treated by any other methods in the future. So I believe that treating those problems early enough appropriately, but somebody who knows the difference between treating and not treating and somebody who can appropriately and safely apply these therapies, makes a world of a difference. It's sad to see these people who come with a completely normal leg, let's say the left leg is completely normal. And the right leg is three times the size, full of varicose veins. These are Caucasian people who have these dark discoloration of the leg from the knee down because of the vein problems that cause these changes in skin color. And not only that, but they are very disabled. They cannot walk. They cannot perform their jobs. If their job, let's say, was a police officer that depends on being on your legs or the mailman, they have to quit their jobs because they cannot carry this huge heavy leg and painful leg for the future. So this has disasters, consequences, personally, financial. I've been aware of marriage that has been broken by this problem and it's a very costly problem.