This chronic swelling can end up in ulcers. This is a complete different topic, it’s called venous ulcers. These venous ulcers that are a huge economic burden to taxpayers. Is that thousands of millions of dollars are dedicated to the care of venous ulcers, it’s enormous and something that is one of the biggest burden for tax dollars in this country. And so if you want to avoid that by a simple intervention that can be done by a needle stick you know, it’s always welcome to be accepted.