There is treatment for Dupuytren's contracture. Having the disease itself does not usually warrant treatment. There are many people who have the genes for Dupuytren's disease, but have no symptoms. There are many people who have symptoms, but they're quite mild and they don't affect hand function. And in any appreciable way, those patients don't require any treatment at all. Once a contracture occurs and loss of motion becomes sufficient that people are affected functionally, they can no longer do what they want to do or what they need to do with their hands, that's when treatment is indicated. Treatment is usually very successful in correcting contractures and restoring motion either fully or significantly. However, even successful treatment is not always permanent. There's a fairly high incidence of recurrence of Dupuytren's contracture after even very successful treatment of any form. Both surgical treatments and non-surgical treatments are available. And all of them have the possibility of recurrence of contracture and functional loss after successful treatment.