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The material used to tie stitches is called suture. There are many types of suture. Most are made of plastic, and some are made from biologic materials, taken from animals. The plastic suture may need to be removed, but others will resorb or biodegrade. Also called dissolvable stitches, the resorbable stitches are designed to fall out after the edges of the skin have healed together. Often one side of the knot will fall out before the other, if this happens, it’s best to let the other side fall out too. But if it’s bothersome, you may gently remove the other end.