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The pills are generally very well tolerated. Some of the side effects that are associated with are headache, flushing, indigestion, lower back pain, but the broad, broad majority of men actually do very well on this, not just from a symptom standpoint, but they tolerate it extremely well, where they’re able to be on these medications and these pills for long periods of time. Currently there’s no data supporting that there’s any long-term damage associated with use of these PD5 inhibitors.