Now you might wonder, so how does one confirm a diagnosis of gastroesophageal reflux disease? Well, it depends. Technically your grandmother could make a diagnosis in an uncomplicated case. In other words, you consume a particular substance. It triggers this burning sensation, or if you bend over, tie your shoes, or pick up an object and this reproducibly causes the heartburn, then that's a pretty good index that you do have gastroesophageal reflux disease. However, the mere fact that individuals have reflux doesn't necessarily mean that they have a disease or a serious condition. That determination one would arrive at because of the fact that it's altering your normal activities. It's making you feel uncomfortable. It's causing you to experience sensations that you don't want at times where it's not convenient for you to feel these things. That's when the diagnosis begins to firm up.