Followup that is required while one is on treatment can vary from clinic to clinic, depending on how each clinic manages their hepatitis C patients. Usually during the course of the treatment, your doctor will ask you to do blood work, to make sure that the treatment is working. And also your office will also likely check in with you from time to time to make sure that you have continued to take your medication daily. And there are no significant side effects from taking the medication. Once you have completed treatment, your doctor will likely do blood work again, to make sure that you have zero viral copy in your blood at that point. And also another blood draw, 12 weeks after you are done with the treatment. If no virus can be detected in your blood at that point, you are considered cured of the infection.