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In the absence of any therapy, if patients are individuals acquire HIV (perhaps 10 years later and no medications or no diagnosis) they may end up with a syndrome known as Acquired Immunodeficiency Syndrome. In this circumstance, these are individuals who are known to have infection with HIV, but their immunity has been destroyed over the intervening years to the point where they’re subject to infections with very uncommon and weak diseases, bacteria, parasites, and other viruses.