Most of the time, hives resolve in 30 minutes to 24 hours on their own. If the symptoms are bothersome, there are medications that you can take over the counter to help with your symptoms. Hives treatment includes anti-histamines such as Cetirizine or diphenhydramine. Sometimes a stronger prescription is recommended. Talk to your doctor if your symptoms are not improving with over the counter remedies. Home remedies for hives include using a cold compress to help with the itching and irritation associated with hives.