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Most nasal polyps occur in the setting of a chronic sinusitis. They occur on both sides of the nose and they’re usually due to inflammation. They are growths of tissue arising from the lining of the nose or sinus cavity. Polyps that occur on only one side of the nose are less common and require more investigation, as they could be a sign of a more aggressive type of polyp, called inverted papilloma, or possibly even a nasal tumor.