Prescription medications to treat overweight and obesity work in different ways. For example, some medications may help you feel less hungry or full, sooner other medications make it harder for your body to absorb fat from the foods you eat. When this is combined with changes to behavior, including eating and physical activity, prescription medications may help. Some patients lose weight. On average people who take prescription medications as part of a lifestyle program lose between three and 9% more of their starting body weight than people in a lifestyle program who do not take medications results vary by medication and by person experts are concerned that in some cases, the side effects of prescription medications to treat overweight and obesity may outweigh the benefits. For this reason, you should never take weight loss medications only to improve the way you look. Current FDA approved weight loss medications include Qsymia Contrave Saxenda. Other medications are still in development.