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Most types of microorganisms can cause sepsis, including bacteria, fungi, viruses, and parasites. While bacteria have been known to most commonly cause sepsis ,it may also be caused by common viral infections, such as seasonal influenza viruses and SARS-CoV-2, the virus leading to COVID-19. Sepsis often presents as the clinical deterioration of common and preventable infections, such as those of the respiratory gastrointestinal and urinary tract, or of wounds and skin. Sepsis is frequently underdiagnosed at an early stage when it is still potentially reversible.