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Why is an upper endoscopy performed? So an upper endoscopy can be performed to evaluate a number of symptoms. These include abdominal pain, weight loss, nausea, vomiting, difficulty swallowing, as well as systemic conditions as iron deficiency anemia. The common results of an upper endoscopy can show things like gastric or duodenal ulcers. These are ulcers that occur in the upper digestive tract. It is a way to diagnose gastric or stomach cancer or esophageal cancer. We also see conditions such as hiatal hernias, or esophageal strictures, which actually can even be dilated or opened up during this procedure. These are just a few things that can be diagnosed. And if symptoms that are worrisome occur, you must seek medical attention.